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MathSoft Inc s-plus professional 4.5, release 2
S Plus Professional 4.5, Release 2, supplied by MathSoft Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s-plus+professional+4%2E5%2C+release+2/s+plus+2000/pm27185297-131-27-29
Average 90 stars, based on 1 article reviews
s-plus professional 4.5, release 2 - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Effectiveness of supersaturation promoting excipients on albendazole concentrations in upper gastrointestinal lumen of fasted healthy adults.
Article Snippet: Article history: Received 24 March 2016 Received in revised form 26 April 2016 Accepted 12 May 2016 Available online 13 May 2016 Purpose: To evaluate the impact of dosage form relevant levels of a polymeric precipitation inhibitor and of lipid excipients on supersaturation of upper gastrointestinal contents with albendazole, a lipophilic weak base.. Materials and methods: Albendazole concentrations in stomach and in duodenumwere evaluated after administration of 1) a suspension in water (Susp-Control), 2) a suspension in water in which hydroxyprolylmethylcellulose E5 (HPMC E5) had been pre-dissolved (Susp-HPMC), and 3) and 4) two contrasting designs of lipid based suspensions dispersed in water (Susp-IIIA and Susp-IV), on a cross-over basis to fasted healthy adults.. Results: Limited, but statistically significant supersaturation of duodenal contentswas observed after Susp-HPMC, Susp-IIIA, and Susp-IV; supersaturation was more consistent after Susp-HPMC administration.



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